Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 18/20 | 0.71 |
| ▸ | HTR2A | P28223 | 15/20 | 0.71 |
| ▸ | HTR1A | P08908 | 14/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728999 | 0.97 | DRD2 (0.70) | DRD2HTR2AHTR1AKCNH2 | |
| SCHEMBL4728953 | 0.95 | DRD2 (0.70) | DRD2HTR2AHTR1AKCNH2 | |
| SCHEMBL4726958 | 0.89 | DRD2 (0.71) | DRD2HTR2AHTR1ASLC6A4KCNH2 | |
| SCHEMBL4727713 | 0.88 | DRD2 (0.72) | DRD2HTR2AHTR1ASLC6A4KCNH2 | |
| SCHEMBL4727243 | 0.86 | DRD2 (0.72) | DRD2HTR2AHTR1ASLC6A4KCNH2 | |
| SCHEMBL4728870 | 0.85 | DRD2 (0.51) | DRD2HTR2AHTR1ASLC6A4 | |
| SCHEMBL4727208 | 0.85 | DRD2 (0.72) | DRD2HTR2AHTR1AKCNH2 | |
| SCHEMBL4729236 | 0.84 | DRD2 (0.52) | DRD2HTR2AHTR1ASLC6A4 | |
| SCHEMBL4729270 | 0.84 | DRD2 (0.71) | DRD2HTR2AHTR1ASLC6A4KCNH2 | |
| SCHEMBL4726930 | 0.83 | DRD2 (0.72) | DRD2HTR2AHTR1AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020306-A2 | ISOINDOLE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2008-02-21 | — | — | WO | claimed |