Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728237 | 0.87 | SLC6A4 (0.51) | EPHX1HDAC8SLC6A4SLC6A3CARM1 | |
| SCHEMBL495855 | 0.83 | HDAC8 (0.50) | EPHX1HDAC8MEN1KMT2ACARM1 | |
| SCHEMBL30239684 | 0.83 | DPP4 (0.44) | MEN1KMT2ASLC6A4SLC6A3TAAR1 | |
| Hydrochloric Acid SCHEMBL496040 | 0.82 | HDAC8 (0.51) | EPHX1HDAC8MEN1KMT2ACARM1 | |
| SCHEMBL3595876 | 0.80 | EPHX1 (0.57) | EPHX1MEN1KMT2AANPEPSLC6A4 | |
| SCHEMBL3594490 | 0.80 | EPHX1 (0.57) | EPHX1MEN1KMT2AANPEPSLC6A4 | |
| SCHEMBL7369953 | 0.80 | EPHX1 (0.57) | EPHX1MEN1KMT2AANPEPSLC6A4 | |
| SCHEMBL7216040 | 0.79 | SLC6A4 (0.56) | EPHX1ANPEPSLC6A4SLC6A3SLC6A2 | |
| SCHEMBL1619274 | 0.79 | SLC6A4 (0.56) | EPHX1ANPEPSLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8267549 | 0.79 | SLC6A4 (0.56) | EPHX1ANPEPSLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008036308-A2 | AMINO-SUBSTITUTED HETEROCYCLES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARMACEUTICALS, LLC (US) | 2008-03-27 | — | — | WO | disclosed |