Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3589379 | 0.89 | NPSR1 (0.50) | NPSR1GFERALDH1A1KDM4EMAPT | |
| SCHEMBL14160287 | 0.88 | NPSR1 (0.48) | NPSR1GFERALDH1A1KDM4EMAPT | |
| SCHEMBL4730681 | 0.81 | NPSR1 (0.54) | NPSR1GFERALDH1A1KDM4EMAPT | |
| SCHEMBL3593810 | 0.81 | NPSR1 (0.66) | NPSR1GFERALDH1A1KDM4EMAPT | |
| SCHEMBL4670934 | 0.80 | NPSR1 (0.54) | NPSR1GFERALDH1A1KDM4EMAPT | |
| SCHEMBL3598116 | 0.80 | NPSR1 (0.52) | NPSR1GFERALDH1A1KDM4EMAPT | |
| SCHEMBL3593442 | 0.80 | NPSR1 (0.52) | NPSR1GFERALDH1A1KDM4EMAPT | |
| SCHEMBL4795285 | 0.80 | NPSR1 (0.49) | NPSR1GFERALDH1A1KDM4EMAPT | |
| SCHEMBL3582210 | 0.78 | NPSR1 (0.51) | NPSR1GFERALDH1A1KDM4EMAPT | |
| SCHEMBL3592318 | 0.76 | NPSR1 (0.49) | NPSR1GFERALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937663-A1 | THIOPHENE DERIVATIVES AS PPAR AGONISTS I | Inpharmatica Limited (GB) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007036730-A1 | THIOPHENE DERIVATIVES AS PPAR AGONISTS I | INPHARMATICA LIMITED (GB) | 2007-04-05 | — | — | WO | disclosed |