Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3587284 | 0.89 | NPSR1 (0.49) | NPSR1GFERALDH1A1MAPTKDM4E | |
| SCHEMBL3593123 | 0.80 | NPSR1 (0.52) | NPSR1GFERALDH1A1MAPTKDM4E | |
| SCHEMBL4730677 | 0.80 | NPSR1 (0.52) | NPSR1GFERALDH1A1MAPTKDM4E | |
| SCHEMBL3585000 | 0.78 | NPSR1 (0.64) | NPSR1GFERALDH1A1MAPTKDM4E | |
| SCHEMBL4730681 | 0.78 | NPSR1 (0.54) | NPSR1GFERALDH1A1MAPTKDM4E | |
| SCHEMBL4674668 | 0.77 | NPSR1 (0.50) | NPSR1GFERALDH1A1MAPTKDM4E | |
| SCHEMBL4670934 | 0.76 | NPSR1 (0.54) | NPSR1GFERALDH1A1MAPTKDM4E | |
| SCHEMBL3596620 | 0.75 | NPSR1 (0.62) | NPSR1GFERALDH1A1MAPTKDM4E | |
| SCHEMBL3586151 | 0.75 | NPSR1 (0.50) | NPSR1GFERALDH1A1MAPTKDM4E | |
| SCHEMBL14160296 | 0.75 | ALDH1A1 (0.51) | NPSR1GFERALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007036730-A9 | THIOPHENE DERIVATIVES AS PPAR AGONISTS I | INPHARMATICA LTD (GB) | 2008-06-19 | — | — | WO | claimed |