Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL714517 | 0.85 | PDE10A (0.36) | ADRA1DPDE10A | |
| SCHEMBL3176688 | 0.81 | AGXT (0.34) | PDE10A | |
| SCHEMBL711097 | 0.76 | — | — | |
| SCHEMBL13528703 | 0.76 | — | — | |
| SCHEMBL712047 | 0.73 | APP (0.38) | APPPDE10A | |
| SCHEMBL712121 | 0.73 | APP (0.38) | APPPDE10A | |
| SCHEMBL712978 | 0.72 | BRS3 (0.49) | — | |
| Water SCHEMBL713364 | 0.72 | APP (0.37) | APPPDE10A | |
| SCHEMBL714888 | 0.71 | WDR5 (0.38) | PDE10A | |
| SCHEMBL714282 | 0.71 | WDR5 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008047849-A1 | PROCESS FOR THE PRODUCTION OF 2- [ [4- T (2, 2-DIMETHYL-1, 3-DIOXAN-5-YL) METHOXY] PYRIDIN-2-YL] METHYLTHIO] -1H-BENZIMIDAZOLE | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2008-04-24 | — | — | WO | disclosed |