Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4730738 | 0.98 | KDM4E (0.54) | KDM4ECYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL7849332 | 0.87 | KDM4E (0.51) | KDM4ECYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL13469244 | 0.86 | KDM4E (0.58) | KDM4ECYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL3230860 | 0.85 | KDM4E (0.61) | KDM4ECYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL26785965 | 0.84 | KDM4E (0.61) | KDM4ECYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL23292486 | 0.83 | KDM4E (0.55) | KDM4ECYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL149036 | 0.83 | KDM4E (0.55) | KDM4ECYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL9952903 | 0.82 | KDM4E (0.54) | KDM4ECYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL2773966 | 0.82 | KDM4E (0.54) | KDM4ECYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL26010170 | 0.81 | LOXL2 (0.56) | KDM4ECA1CA2L3MBTL1KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020306-A2 | ISOINDOLE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2008-02-21 | — | — | WO | disclosed |