Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of 1,3-Propanediol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,3-Propanediol SCHEMBL3765570 | 1.00 | — | — | |
| 1,3-Propanediol SCHEMBL1840455 | 1.00 | CA5A (0.57) | CA5ACA5BALDH1A1TDP1LMNA | |
| 1,4-Butanediol SCHEMBL1220765 | 0.93 | CA5A (0.57) | CA5ACA5BALDH1A1TDP1LMNA | |
| 1,4-Butanediol SCHEMBL9322154 | 0.93 | CA5A (0.57) | CA5ACA5BALDH1A1TDP1LMNA | |
| 1,4-Butanediol SCHEMBL167828 | 0.93 | CA5A (0.57) | CA5ACA5BALDH1A1TDP1LMNA | |
| Nitric Acid SCHEMBL25264224 | 0.90 | CA5A (0.53) | CA5ACA5BALDH1A1TDP1LMNA | |
| Nitric Acid SCHEMBL25202723 | 0.90 | CA5A (0.53) | CA5ACA5BALDH1A1TDP1LMNA | |
| Nitric Acid SCHEMBL9874805 | 0.90 | CA5A (0.53) | CA5ACA5BALDH1A1TDP1LMNA | |
| Nitric Acid SCHEMBL25180692 | 0.90 | CA5A (0.53) | CA5ACA5BALDH1A1TDP1LMNA | |
| Nitric Acid SCHEMBL25180668 | 0.90 | CA5A (0.53) | CA5ACA5BALDH1A1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3044190-B1 | BURN RATE MODIFIER | THALES AUSTRALIA LTD (AU) | 2024-07-03 | — | — | EP | claimed |
| EP-3044191-B1 | BURN RATE MODIFIER | THALES AUSTRALIA LTD (AU) | 2019-11-20 | — | — | EP | claimed |
| US-20190210938-A1 | PROPELLANT STABILIZER | THALES AUSTRALIA LIMITED (AU) | 2019-07-11 | — | — | US | claimed |
| US-10196323-B2 | Burn rate modifier | THALES AUSTRALIA LIMITED (AU) | 2019-02-05 | — | — | US | claimed |
| US-10087116-B2 | Burn rate modifier | THALES AUSTRALIA LIMITED (AU) | 2018-10-02 | — | — | US | claimed |
| US-20160244382-A1 | BURN RATE MODIFIER | THALES AUSTRALIA LIMITED (AU) | 2016-08-25 | — | — | US | claimed |
| US-20160221888-A1 | BURN RATE MODIFIER | THALES AUSTRALIA LIMITED (AU) | 2016-08-04 | — | — | US | claimed |
| US-20160221889-A1 | BURN RATE MODIFIER | THALES AUSTRALIA LIMITED (AU) | 2016-08-04 | — | — | US | claimed |
| EP-3049376-A1 | BURN RATE MODIFIER | Thales Australia Limited (AU) | 2016-08-03 | — | — | EP | claimed |
| EP-3044191-A1 | BURN RATE MODIFIER | Thales Australia Limited (AU) | 2016-07-20 | — | — | EP | claimed |
| WO-2015035457-A1 | BURN RATE MODIFIER | THALES AUSTRALIA LIMITED (AU) | 2015-03-19 | — | — | WO | claimed |
| WO-2015035458-A1 | BURN RATE MODIFIER | THALES AUSTRALIA LIMITED (AU) | 2015-03-19 | — | — | WO | claimed |
| EP-1196360-A2 | FAMILY OF PROPELLANT COMPOSITIONS AND METHOD | ATLANTIC RESEARCH CORPORATION (US) | 2002-04-17 | — | — | EP | claimed |
| WO-2000063139-A2 | FAMILY OF PROPELLANT COMPOSITIONS AND METHOD | ATLANTIC RESEARCH CORPORATION (US) | 2000-10-26 | — | — | WO | claimed |
| US-5316600-A | HMX, RDX or glycidyl azide polymer and isocyanate compounds | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1994-05-31 | — | — | US | claimed |
| EP-0313696-A1 | Diesel fuel with improved cetane number and containing polynitrate esters and stabilizers | MOBIL OIL CORPORATION (US) | 1989-05-03 | — | — | EP | claimed |
| US-4746326-A | Cetane number of diesel fuel by incorporating polynitrate esters and stabilizers | MOBIL OIL CORPORATION (US) | 1988-05-24 | — | — | US | claimed |
| US-4705534-A | Cetane number of diesel fuel by incorporating polynitrate esters and stabilizers | MOBIL OIL CORPORATION (US) | 1987-11-10 | — | — | US | claimed |
| US-4507161-A | OXYGEN RELEASING SALT, EMULSIFIERS | ICI AUSTRALIA LIMITED (AU) | 1985-03-26 | — | — | US | claimed |
| US-3977922-A | NITRO COMPOUNDS IN THERMOSETTING RESINS | NIPPON OILS AND FATS COMPANY LIMITED (JA) | 1976-08-31 | — | — | US | claimed |