Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729679 | 0.90 | UTS2R (0.61) | UTS2RNPC1ALDH1A1OPRM1OPRD1 | |
| SCHEMBL4731222 | 0.90 | UTS2R (0.64) | UTS2RALDH1A1OPRM1OPRD1SMN1; SMN2 | |
| SCHEMBL4730453 | 0.87 | NPC1 (0.60) | UTS2RNPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL4730847 | 0.86 | UTS2R (0.58) | UTS2RNPC1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL4731066 | 0.85 | UTS2R (0.63) | UTS2RNPC1ALDH1A1OPRM1OPRD1 | |
| SCHEMBL4731281 | 0.84 | UTS2R (0.62) | UTS2RNPC1OPRM1OPRD1SMN1; SMN2 | |
| SCHEMBL4731502 | 0.81 | UTS2R (0.55) | UTS2RNPC1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL4730705 | 0.80 | UTS2R (0.65) | UTS2RALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL4732375 | 0.77 | UTS2R (0.65) | UTS2RALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL4734176 | 0.77 | UTS2R (0.60) | UTS2RNPC1SMN1; SMN2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057543-A2 | UII-MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2008-05-15 | — | — | WO | claimed |
| WO-2008057543-A2 | UII-MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2008-05-15 | — | — | WO | disclosed |