Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.64 |
| ▸ | CNR1 | P21554 | 4/20 | 0.64 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | WNT1 | P04628 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731049 | 0.89 | CNR2 (0.61) | CNR2CNR1 | |
| SCHEMBL4734575 | 0.89 | CNR2 (0.78) | CNR2CNR1BRD4GSK3BDYRK1A | |
| SCHEMBL4734972 | 0.88 | CNR2 (0.62) | CNR2CNR1BRD4 | |
| SCHEMBL4729964 | 0.88 | CNR2 (0.82) | CNR2CNR1 | |
| SCHEMBL14206639 | 0.87 | CNR2 (0.59) | CNR2CNR1GSK3BDYRK1AWNT1 | |
| SCHEMBL4730417 | 0.86 | CNR2 (0.60) | CNR2CNR1 | |
| SCHEMBL14206656 | 0.86 | CNR2 (0.57) | CNR2CNR1 | |
| SCHEMBL4732966 | 0.81 | CNR2 (0.80) | CNR2CNR1BRD4 | |
| SCHEMBL4731510 | 0.81 | CNR2 (0.55) | CNR2CNR1BRD4 | |
| SCHEMBL14206637 | 0.80 | CNR2 (0.54) | CNR2CNR1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |