Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 16/20 | 0.62 |
| ▸ | CNR1 | P21554 | 5/20 | 0.62 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730074 | 0.89 | CNR2 (0.77) | CNR2CNR1 | |
| SCHEMBL4731207 | 0.88 | CNR2 (0.64) | CNR2CNR1BRD4 | |
| SCHEMBL4729964 | 0.87 | CNR2 (0.82) | CNR2CNR1 | |
| SCHEMBL4731049 | 0.86 | CNR2 (0.61) | CNR2CNR1 | |
| SCHEMBL14206639 | 0.84 | CNR2 (0.59) | CNR2CNR1RIPK1 | |
| SCHEMBL4782349 | 0.83 | CNR2 (0.71) | CNR2CNR1 | |
| SCHEMBL14206656 | 0.83 | CNR2 (0.57) | CNR2CNR1 | |
| SCHEMBL4730417 | 0.83 | CNR2 (0.60) | CNR2CNR1 | |
| SCHEMBL4731510 | 0.80 | CNR2 (0.55) | CNR2CNR1BRD4RIPK1 | |
| SCHEMBL14206637 | 0.79 | CNR2 (0.54) | CNR2CNR1BRD4RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | claimed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |