Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GBA1 | P04062 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | TACR2 | P21452 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1438737 | 0.90 | SMN1; SMN2 (0.53) | SMN1; SMN2GBA1TACR2GAAKDM4E | |
| SCHEMBL23855249 | 0.88 | SMN1; SMN2 (0.53) | SMN1; SMN2BCHEGAALTA4HKDM2B | |
| SCHEMBL4730783 | 0.88 | SMN1; SMN2 (0.53) | SMN1; SMN2BCHEGAALTA4HKDM2B | |
| SCHEMBL24003548 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2BCHEGAALTA4HKDM4E | |
| SCHEMBL22359167 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2GBA1BCHEGAALTA4H | |
| SCHEMBL22359168 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2BCHEGAALTA4HKDM4E | |
| SCHEMBL4035398 | 0.77 | SMN1; SMN2 (0.62) | SMN1; SMN2GAAKDM4E | |
| SCHEMBL31377131 | 0.76 | GBA1 (0.49) | GBA1TACR2OPRM1KDM2B | |
| Hydrochloric Acid SCHEMBL27659724 | 0.75 | SMN1; SMN2 (0.60) | SMN1; SMN2GAAKDM4E | |
| SCHEMBL1794055 | 0.75 | SMN1; SMN2 (0.44) | SMN1; SMN2BCHEGAAKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045564-A2 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2008-04-17 | — | — | WO | disclosed |