SCHEMBL4731335

SCHEMBL4731335

CCC/C(=N/O)c1ccc(OC(CC)C(=O)O)cc1

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.55
PPARG P37231 19/20 0.49
PPARA Q07869 19/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4726473 0.89 SMN1; SMN2 (0.57) SMN1; SMN2PPARGPPARA
SCHEMBL4726475 0.89 SMN1; SMN2 (0.57) SMN1; SMN2PPARGPPARA
SCHEMBL4728216 0.83 PPARA (0.50) SMN1; SMN2PPARGPPARA
SCHEMBL5010216 0.82 SMN1; SMN2 (0.56) SMN1; SMN2PPARGPPARA
SCHEMBL6113119 0.80 SMN1; SMN2 (0.54) SMN1; SMN2PPARGPPARA
SCHEMBL6113115 0.80 SMN1; SMN2 (0.54) SMN1; SMN2PPARGPPARA
SCHEMBL2231218 0.79 SMN1; SMN2 (0.63) SMN1; SMN2PPARGPPARA
SCHEMBL2561889 0.77 PPARG (0.68) SMN1; SMN2PPARGPPARA
Methane SCHEMBL27838357 0.77 SMN1; SMN2 (0.61) SMN1; SMN2PPARGPPARA
SCHEMBL5004494 0.77 SMN1; SMN2 (0.54) SMN1; SMN2PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO claimed
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO disclosed