SCHEMBL4731340

SCHEMBL4731340

CCC(Oc1ccc(CCCC=NO)cc1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 18/20 0.51
PPARG P37231 18/20 0.51
SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4729667 0.92 SMN1; SMN2 (0.50) PPARAPPARGSMN1; SMN2
SCHEMBL27596214 0.85 PPARA (0.55) PPARAPPARGSMN1; SMN2
SCHEMBL4728218 0.82 PPARA (0.47) PPARAPPARGSMN1; SMN2
SCHEMBL6064663 0.81 PPARA (0.58) PPARAPPARGSMN1; SMN2
SCHEMBL28886753 0.80 PPARA (0.72) PPARAPPARGSMN1; SMN2
SCHEMBL8387983 0.80 SMN1; SMN2 (0.54) PPARAPPARGSMN1; SMN2
SCHEMBL28381180 0.80 PPARA (0.72) PPARAPPARGSMN1; SMN2
SCHEMBL28381512 0.80 PPARA (0.72) PPARAPPARGSMN1; SMN2
SCHEMBL5830085 0.76 SMN1; SMN2 (0.56) PPARAPPARGSMN1; SMN2
SCHEMBL8935920 0.76 PPARG (0.71) PPARAPPARGSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO claimed
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO disclosed