SCHEMBL4731422

SCHEMBL4731422

CC(C)C(C(=O)OC(CC(=O)O)(CC(=O)O)C(=O)O)(C(C)C)C(C)C

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.37
HIF1A Q16665 2/20 0.37
CYP2D6 P10635 1/20 0.37
TSHR P16473 1/20 0.37
ALDH1A1 P00352 1/20 0.33
HMGCR P04035 1/20 0.33
CHRM1 P11229 1/20 0.33
TBXA2R P21731 1/20 0.33
ADRA1A P35348 1/20 0.33
CPT2 P23786 1/20 0.31
ACLY P53396 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4731097 0.79 CYP2C19 (0.44) CYP2C19HIF1ACYP2D6TSHRALDH1A1
SCHEMBL9837410 0.78 CYP2C19 (0.38) CYP2C19HIF1ACYP2D6TSHRALDH1A1
SCHEMBL653302 0.76 CYP2C19 (0.37) CYP2C19HIF1ACYP2D6TSHRALDH1A1
SCHEMBL997778 0.76 CYP2C19 (0.37) CYP2C19HIF1ACYP2D6TSHRALDH1A1
SCHEMBL12485746 0.75 ALDH1A1 (0.52) CYP2C19HIF1ACYP2D6TSHRALDH1A1
SCHEMBL10476520 0.75 TSHR (0.39) CYP2C19HIF1ACYP2D6TSHRALDH1A1
SCHEMBL9387459 0.74 CYP2D6 (0.35) CYP2C19HIF1ACYP2D6TSHRALDH1A1
SCHEMBL20521418 0.74 CYP2D6 (0.35) CYP2C19HIF1ACYP2D6TSHRALDH1A1
SCHEMBL2971627 0.74 CYP2D6 (0.35) CYP2C19HIF1ACYP2D6TSHRALDH1A1
SCHEMBL28564581 0.74 CYP2D6 (0.35) CYP2C19HIF1ACYP2D6TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008043654-A2 BLOND CLEAR TREATMENT HENKEL AG & CO. KGAA (DE) 2008-04-17 WO disclosed