Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 1.00 |
| ▸ | MAOA | P21397 | 11/20 | 0.82 |
| ▸ | NPC1 | O15118 | 3/20 | 0.72 |
| ▸ | RAB9A | P51151 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | GRM5 | P41594 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21213879 | 0.90 | MAOB (1.00) | MAOBMAOANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11613149 | 0.84 | MAOB (0.73) | MAOBMAOANPC1RAB9AHPGD | |
| SCHEMBL11698521 | 0.83 | MAOB (0.71) | MAOBMAOANPC1RAB9AALDH1A1 | |
| SCHEMBL11559934 | 0.81 | MAOB (0.68) | MAOBMAOANPC1RAB9AALDH1A1 | |
| SCHEMBL11663617 | 0.81 | MAOB (0.68) | MAOBMAOANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8672485 | 0.81 | MAOB (1.00) | MAOBMAOANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12502194 | 0.81 | MAOB (0.68) | MAOBMAOANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7910955 | 0.81 | MAOB (0.66) | MAOBMAOANPC1RAB9A | |
| SCHEMBL1697225 | 0.81 | MAOB (0.68) | MAOBMAOANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16892161 | 0.80 | RAB9A (0.68) | MAOBMAOANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008046084-A2 | SPIROHETEROCYCLIC COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2008-04-17 | — | — | WO | disclosed |
| US-5028720-A | 6,7-nonsubstituted and 6,7-disubstituted-3,4-dihydroxy benzopyran-2H-one compounds having antiaggregatory properties and processes for their preparation | OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1991-07-02 | — | — | US | disclosed |
| US-4845121-A | Aci-reductone compounds belonging to the 6,7-disubstituted-3,4-dihydro benzopyan-2H-one class having antiaggregatory properties | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1989-07-04 | — | — | US | disclosed |