Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 7/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732240 | 1.00 | CYP3A4 (0.35) | CYP3A4TSHRTDP1ATMCA2 | |
| SCHEMBL4783452 | 0.91 | CYP3A4 (0.35) | CYP3A4TSHRTDP1ATMCA2 | |
| SCHEMBL4783443 | 0.91 | CYP3A4 (0.35) | CYP3A4TSHRTDP1ATMCA2 | |
| SCHEMBL4732190 | 0.89 | CYP3A4 (0.37) | CYP3A4TSHRTDP1ATMCA2 | |
| SCHEMBL4732187 | 0.89 | CYP3A4 (0.37) | CYP3A4TSHRTDP1ATMCA2 | |
| SCHEMBL4729107 | 0.81 | ALDH1A1 (0.41) | CYP3A4TSHRCA2MAPK1ALDH1A1 | |
| SCHEMBL4729114 | 0.81 | ALDH1A1 (0.41) | CYP3A4TSHRCA2MAPK1ALDH1A1 | |
| SCHEMBL4733217 | 0.79 | FNTA (0.39) | ALDH1A1 | |
| SCHEMBL4733215 | 0.79 | FNTA (0.39) | ALDH1A1 | |
| SCHEMBL4733390 | 0.76 | FNTA (0.47) | TSHRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080250739-A1 | FOAMED PLASTIC STRUCTURES | NOVA CHEMICALS INC. (US) | 2008-10-16 | — | — | US | disclosed |
| WO-2008057705-A1 | FOAMED PLASTIC STRUCTURES | NOVA CHEMICALS INC. (US) | 2008-05-15 | — | — | WO | disclosed |
| EP-0785964-B1 | NON-LINEAR STYRENIC POLYMER-BASED FOAMS | DOW CHEMICAL CO (US) | 1999-04-14 | — | — | EP | disclosed |
| US-5830924-A | LOW DENSITY CLOSED CELL, BLOWING AGENTS | THE DOW CHEMICAL COMPANY (US) | 1998-11-03 | — | — | US | disclosed |