Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.37 |
| ▸ | PPARG | P37231 | 6/20 | 0.37 |
| ▸ | PPARD | Q03181 | 6/20 | 0.37 |
| ▸ | PPARA | Q07869 | 6/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4433665 | 0.83 | GRIK1 (0.47) | CES1CES2APEX1GRIK1EP300 | |
| SCHEMBL285080 | 0.83 | GRIK1 (0.47) | CES1CES2APEX1GRIK1EP300 | |
| SCHEMBL7556833 | 0.83 | GRIK1 (0.47) | CES1CES2APEX1GRIK1EP300 | |
| SCHEMBL4375273 | 0.81 | GRIK1 (0.58) | CES1CES2APEX1GRIK1EP300 | |
| SCHEMBL7562280 | 0.81 | GRIK1 (0.58) | CES1CES2APEX1GRIK1EP300 | |
| SCHEMBL7559357 | 0.81 | GRIK1 (0.52) | CES1CES2APEX1GRIK1EP300 | |
| SCHEMBL984849 | 0.81 | CES1 (0.42) | CES1CES2APEX1GRIK1EP300 | |
| SCHEMBL811158 | 0.81 | GRIK1 (0.58) | CES1CES2APEX1GRIK1EP300 | |
| SCHEMBL811600 | 0.81 | GRIK1 (0.52) | CES1CES2APEX1GRIK1EP300 | |
| SCHEMBL4791448 | 0.80 | APEX1 (0.39) | CES1CES2APEX1GRIK1EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053000-A1 | FLOOR COVERING FOR ANIMAL STALLS | SIKA TECHNOLOGY AG (CH) | 2008-05-08 | — | — | WO | disclosed |