Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731984 | 1.00 | HSP90AA1 (0.53) | HSP90AA1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL4732709 | 1.00 | HSP90AA1 (0.53) | HSP90AA1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL14166663 | 0.96 | HSP90AA1 (0.48) | HSP90AA1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL8292801 | 0.96 | HSP90AA1 (0.53) | HSP90AA1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL8292803 | 0.96 | HSP90AA1 (0.53) | HSP90AA1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL16076994 | 0.93 | HSP90AA1 (0.47) | HSP90AA1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL765884 | 0.92 | HSP90AA1 (0.46) | HSP90AA1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL10170685 | 0.92 | HSP90AA1 (0.46) | HSP90AA1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL19049760 | 0.90 | GPR84 (0.57) | MEN1KMT2AEPHX2GPR84PPARG | |
| SCHEMBL1519481 | 0.90 | GPR84 (0.57) | MEN1KMT2AEPHX2GPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008044033-A1 | AMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2008-04-17 | — | — | WO | disclosed |