Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 13/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730586 | 0.91 | TACR1 (0.34) | TACR1HSD11B1SLC6A4TSHRCYP3A4 | |
| SCHEMBL4729719 | 0.88 | CCR2 (0.37) | TACR1SLC6A4CETPTSHRCYP3A4 | |
| SCHEMBL4731403 | 0.85 | TACR1 (0.33) | TACR1HSD11B1 | |
| SCHEMBL4732208 | 0.85 | CCR2 (0.36) | TACR1SLC6A4CETPTSHRCYP3A4 | |
| SCHEMBL4729389 | 0.84 | CCR2 (0.36) | TACR1HSD11B1SLC6A4 | |
| SCHEMBL4730370 | 0.84 | TACR1 (0.35) | TACR1HSD11B1SLC6A4CETPTSHR | |
| SCHEMBL4728127 | 0.83 | CCR2 (0.36) | TACR1SLC6A4 | |
| SCHEMBL4728688 | 0.83 | CCR2 (0.36) | TACR1SLC6A4 | |
| SCHEMBL4732027 | 0.80 | TACR1 (0.38) | TACR1HSD11B1SLC6A4CYP2D6 | |
| SCHEMBL4731956 | 0.80 | TACR1 (0.46) | TACR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045564-A2 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2008-04-17 | — | — | WO | disclosed |