Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.61 |
| ▸ | AADAC | P22760 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | HTR6 | P50406 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13695984 | 1.00 | AR (0.61) | ARCYP3A4LMNACES2ABCB11 | |
| SCHEMBL14086872 | 1.00 | AR (0.61) | ARCYP3A4LMNACES2ABCB11 | |
| SCHEMBL17768285 | 0.91 | LMNA (0.56) | ARCYP3A4LMNACES2ABCB11 | |
| SCHEMBL14086874 | 0.86 | AR (0.54) | ARCYP3A4LMNACES2ABCB11 | |
| SCHEMBL6815986 | 0.82 | AR (0.73) | ARCYP3A4LMNACES2ABCB11 | |
| SCHEMBL20112813 | 0.81 | LMNA (0.62) | ARLMNA | |
| SCHEMBL201864 | 0.79 | AR (0.48) | ARCYP3A4LMNACES2ABCB11 | |
| SCHEMBL13244699 | 0.78 | AR (0.48) | ARCYP3A4LMNACES2ABCB11 | |
| SCHEMBL201851 | 0.78 | AR (0.55) | ARCYP3A4LMNACES2ABCB11 | |
| SCHEMBL4959122 | 0.78 | AR (0.71) | ARCYP3A4LMNACES2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016079522-A1 | ANDROGEN RECEPTOR MODULATORS AND THEIR USE AS ANTI-CANCER AGENTS | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2016-05-26 | — | — | WO | disclosed |
| WO-2008044033-A1 | AMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2008-04-17 | — | — | WO | disclosed |
| US-6828458-B2 | Topical antiandrogen for hair loss and other hyperandrogenic conditions | BIOPHYSICA, INC. | 2004-12-07 | — | — | US | disclosed |
| US-6472415-B1 | Androgen receptor suppressors in the therapy and diagnosis of prostate cancer, alopecia and other hyper-androgenic syndromes | BIOPHYSICA, INC. | 2002-10-29 | — | — | US | disclosed |
| US-6184249-B1 | Androgen receptor suppressors in the therapy and diagnosis of prostate cancer, alopecia and other hyper-androgenic syndromes | BIOPHYSICA, INC. | 2001-02-06 | — | — | US | disclosed |
| US-4636505-A | ANTIANDROGENS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-01-13 | — | — | US | disclosed |
| EP-0100172-A1 | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-02-08 | — | — | EP | disclosed |