SCHEMBL4733019

SCHEMBL4733019

C/C=C/C(=O)C1=C(CC)CCCC1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.35
THRB P10828 1/20 0.35
GSTP1 P09211 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4733020 1.00 THRA (0.35) THRATHRBGSTP1
SCHEMBL4734422 0.98 THRA (0.34) THRATHRBGSTP1
SCHEMBL4734419 0.98 THRA (0.34) THRATHRBGSTP1
SCHEMBL313675 0.81 MEN1 (0.32) GSTP1
SCHEMBL313676 0.81 MEN1 (0.32) GSTP1
SCHEMBL4783884 0.75 KDM4E (0.32)
SCHEMBL4783887 0.75 KDM4E (0.32)
SCHEMBL3401365 0.75 GSTP1 (0.33) THRATHRBGSTP1
SCHEMBL3401363 0.75 GSTP1 (0.33) THRATHRBGSTP1
SCHEMBL4738201 0.74 KDM4E (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008071025-A1 CYCLOALKENYL BUTENONES AND FRAGRANCE COMPOSITIONS COMPRISING THEM GIVAUDAN SA (CH) 2008-06-19 WO claimed
WO-2008071025-A1 CYCLOALKENYL BUTENONES AND FRAGRANCE COMPOSITIONS COMPRISING THEM GIVAUDAN SA (CH) 2008-06-19 WO disclosed