Phosphoric Acid

Phosphoric Acid

SCHEMBL4733558

O=P([O-])(O)O.O=P([O-])(O)O.O=P([O-])(O)O.O=P([O-])(O)O.[Ca+2].[Ca+2]

nearest known ligand 0.80

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC34A1 Q06495 1/20 0.80
LMNA P02545 2/20 0.43
CA2 P00918 1/20 0.42
KDM4E B2RXH2 2/20 0.41
CYP2C19 P33261 1/20 0.41
KMT2A Q03164 1/20 0.41
FDPS P14324 3/20 0.36
MMP2 P08253 1/20 0.36
THRB P10828 1/20 0.36
MAPK1 P28482 1/20 0.36
HSD17B10 Q99714 1/20 0.36
BLM P54132 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CA1 P00915 2/20 0.32
CA4 P22748 2/20 0.32
CA5A P35218 2/20 0.32
CA5B Q9Y2D0 2/20 0.32
TYMS P04818 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL19326716 1.00 SLC34A1 (0.80) SLC34A1LMNACA2KDM4ECYP2C19
Phosphoric Acid SCHEMBL7943344 1.00 SLC34A1 (0.80) SLC34A1LMNACA2KDM4ECYP2C19
Phosphoric Acid SCHEMBL74378 1.00 SLC34A1 (0.80) SLC34A1LMNACA2KDM4ECYP2C19
Phosphoric Acid SCHEMBL113721 0.95
Phosphoric Acid SCHEMBL119879 0.95
Phosphoric Acid SCHEMBL210340 0.95 SLC34A1 (0.73) SLC34A1LMNACA2KDM4ECYP2C19
Phosphoric Acid SCHEMBL7792643 0.95
Phosphoric Acid SCHEMBL193060 0.95 SLC34A1 (0.73) SLC34A1LMNACA2KDM4ECYP2C19
Phosphoric Acid SCHEMBL19086896 0.95 SLC34A1 (0.73) SLC34A1LMNACA2KDM4ECYP2C19
Phosphoric Acid SCHEMBL29581355 0.95 SLC34A1 (0.73) SLC34A1LMNACA2KDM4ECYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230263935-A1 NON-FIXED TYPE IMPLANT FOR CRANIOTOMY AND METHOD OF MANUFACTURING SAME T&R BIOFAB CO., LTD. (KR) 2023-08-24 US claimed
EP-4190281-A1 NON-FIXED TYPE IMPLANT FOR CRANIOTOMY AND METHOD OF MANUFACTURING SAME T&R Biofab Co., Ltd. (KR) 2023-06-07 EP claimed
US-20170142993-A1 CREATINE-PROTEIN MATRIX AND METHOD FOR PRODUCING SAID MATRIX ALZCHEM AG (DE) 2017-05-25 US claimed
EP-2926669-B1 Creatine protein matrix and method for manufacturing the same ALZCHEM AG (DE) 2017-05-24 EP claimed
EP-2720552-B1 PROCESS FOR THE MANUFACTURE OF A LEAVENED FOODSTUFF AND AN APPARATUS THEREFOR MACPHIE OF GLENBERVIE LTD (GB) 2016-07-13 EP claimed
WO-2015150275-A1 CREATINE-PROTEIN MATRIX AND METHOD FOR PRODUCING SAID MATRIX ALZCHEM AG (DE) 2015-10-08 WO claimed
EP-2926669-A1 Creatine protein matrix and method for manufacturing the same AlzChem AG (DE) 2015-10-07 EP claimed
CN-109487323-A A kind of electrolyte in surface of metal titanium differential arc oxidation preparation perforated membrane containing biological active elements 大连理工大学 2019-03-19 CN disclosed
CN-109384210-A A method of utilizing hydrochloric acid and Phosphate Rock acid calcium salt and calcium sulfate 川恒生态科技有限公司 2019-02-26 CN disclosed
CN-105819769-B A kind of preparation method of pervious cement soil 东南大学 2018-05-04 CN disclosed
US-20170142993-A1 CREATINE-PROTEIN MATRIX AND METHOD FOR PRODUCING SAID MATRIX ALZCHEM AG (DE) 2017-05-25 US disclosed
EP-2926669-B1 Creatine protein matrix and method for manufacturing the same ALZCHEM AG (DE) 2017-05-24 EP disclosed
WO-2015150275-A1 CREATINE-PROTEIN MATRIX AND METHOD FOR PRODUCING SAID MATRIX ALZCHEM AG (DE) 2015-10-08 WO disclosed
EP-2926669-A1 Creatine protein matrix and method for manufacturing the same AlzChem AG (DE) 2015-10-07 EP disclosed
US-20080268045-A1 SUSTAINED RELEASE METHOTREXATE FORMULATIONS AND METHODS OF USE THEREOF PROPRIUS PHARMACEUTICALS, INC. (US) 2008-10-30 US disclosed
WO-2008058288-A2 SUSTAINED RELEASE METHOTREXATE FORMULATIONS AND METHODS OF USE THEREOF PROPRIUS PHARMACEUTICALS, INC. (US) 2008-05-15 WO disclosed
EP-1755697-A2 COMPRESSED POROUS MATERIALS SUITABLE FOR IMPLANT KENSEY NASH CORPORATION (US) 2007-02-28 EP disclosed
WO-2005107829-A2 COMPRESSED POROUS MATERIALS SUITABLE FOR IMPLANT KENSEY NASH CORPORATION (US) 2005-11-17 WO disclosed
US-6242004-B1 CONTAINING POLYMER MODIFIED BY MALEIC ANHYDRIDE PERMATEC TECHNOLOGIE AG (CH) 2001-06-05 US disclosed