SCHEMBL4733767

SCHEMBL4733767

CC(C)(C)C(Cl)C=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5525873 1.00
SCHEMBL15743384 0.71
SCHEMBL28438556 0.71
SCHEMBL2637176 0.69 ALDH1A1 (0.35)
SCHEMBL11389734 0.69
SCHEMBL2951634 0.67
SCHEMBL3908634 0.65
SCHEMBL4050156 0.65
SCHEMBL652266 0.62
SCHEMBL3284394 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9169282-B2 Metal complexes MERCK PATENT GMBH (DE) 2015-10-27 US disclosed
US-9169282-B2 Metal complexes MERCK PATENT GMBH (DE) 2015-10-27 US disclosed
US-8481574-B2 (2Z)-2-(3-butyl-4,5-dimethyl-1,3-thiazol-2(3H)-ylidene)-1-(5-chloro-2-methoxyphenyl)ethanone; antiinflammatory, analgesic agent; autoimmune diseases; neuroprotectants ABBOTT LABORATORIES (US) 2013-07-09 US disclosed
US-20110284799-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2011-11-24 US disclosed
US-20110284799-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2011-11-24 US disclosed
WO-2010086089-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2010-08-05 WO disclosed
US-20080255123-A1 NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS ABBOTT LABORATORIES (US) 2008-10-16 US disclosed
WO-2008063781-A2 CHEMICAL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS ABBOTT LABORATORIES (US) 2008-05-29 WO disclosed
US-20070276142-A1 Catalytic Asymmetric Synthesis of Optically Active Alpha-Halo-Carbonyl Compounds CHEMINOVA A/S (DK) 2007-11-29 US disclosed
EP-1698646-B1 Photocurable composition and photocurable compound DAINIPPON INK & CHEMICALS (JP) 2007-11-21 EP disclosed
EP-1716088-A1 CATALYTIC ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE ALPHA-HALO-CAR BONYL COMPOUNDS Cheminova A/S (DK) 2006-11-02 EP disclosed
EP-1698646-A1 Photocurable composition and photocurable compound DAINIPPON INK AND CHEMICALS, INC. (JP) 2006-09-06 EP disclosed
WO-2005080298-A1 CATALYTIC ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE α-HALO-CARBONYL COMPOUNDS CHEMINOVA A/S (DK) 2005-09-01 WO disclosed
EP-0363582-A1 Substituted dioxolanes BAYER AG (DE) 1990-04-18 EP disclosed
EP-0339390-A1 Herbicidal 2,5-dihydropyrroles NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-11-02 EP disclosed
EP-0134464-B1 PROCESS FOR THE PREPARATION OF 3,3- OR 2,3-DIMETHYL BUTENE AND 2,3- DIMETHYL BUTADIENE OR FOR THE SIMULTANEOUS PREPARATION OF THESE OLEFINS AND GLYCOL OR POLYGLYCOL-N-ALKYL-3,3- OR 2,3-DIMETHYL BUTYL ETHER FROM MONO- AND DICHLORO-DIMETHYL BUTANE HÜLS AKTIENGESELLSCHAFT (DE) 1988-04-20 EP disclosed
EP-0039308-A1 Cyclobutanoxime carbamates, process for their preparation and their use as pesticides, and also the cyclobutanoximes used as intermediates CIBA-GEIGY AG (CH) 1981-11-04 EP disclosed