Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.45 |
| ▸ | CNR1 | P21554 | 3/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783553 | 0.88 | CNR2 (0.53) | CNR2CNR1RIPK1NPC1RAB9A | |
| SCHEMBL14206962 | 0.81 | CNR2 (0.45) | CNR2CNR1RIPK1 | |
| SCHEMBL14206639 | 0.80 | CNR2 (0.59) | CNR2CNR1RIPK1ALDH1A1 | |
| SCHEMBL4733593 | 0.79 | CNR2 (0.52) | CNR2CNR1RIPK1NPC1RAB9A | |
| SCHEMBL4731510 | 0.78 | CNR2 (0.55) | CNR2CNR1RIPK1NPC1RAB9A | |
| SCHEMBL14206637 | 0.77 | CNR2 (0.54) | CNR2CNR1RIPK1L3MBTL1ALDH1A1 | |
| SCHEMBL4732572 | 0.77 | CNR2 (0.46) | CNR2CNR1RIPK1NPC1RAB9A | |
| SCHEMBL14206662 | 0.76 | CNR2 (0.56) | CNR2CNR1RIPK1 | |
| SCHEMBL4734267 | 0.76 | CNR2 (0.50) | CNR2CNR1RIPK1NPC1RAB9A | |
| SCHEMBL4730027 | 0.75 | CNR2 (0.42) | CNR2CNR1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |