Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.52 |
| ▸ | CNR1 | P21554 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783553 | 0.88 | CNR2 (0.53) | CNR2CNR1L3MBTL1NPC1RAB9A | |
| SCHEMBL4734267 | 0.86 | CNR2 (0.50) | CNR2CNR1L3MBTL1NPC1RAB9A | |
| SCHEMBL4732697 | 0.83 | CNR2 (0.53) | CNR2CNR1BCHEACHE | |
| SCHEMBL4733798 | 0.79 | CNR2 (0.45) | CNR2CNR1L3MBTL1NPC1RAB9A | |
| SCHEMBL4733693 | 0.79 | CNR2 (0.53) | CNR2CNR1MEN1KMT2A | |
| SCHEMBL14207105 | 0.77 | CNR2 (0.64) | CNR2CNR1RIPK1 | |
| SCHEMBL4730715 | 0.75 | CNR2 (0.52) | CNR2CNR1RIPK1 | |
| SCHEMBL4730710 | 0.75 | CNR2 (0.52) | CNR2CNR1RIPK1 | |
| SCHEMBL4730818 | 0.74 | CNR2 (0.61) | CNR2CNR1 | |
| SCHEMBL4729966 | 0.74 | CNR2 (0.41) | CNR2CNR1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | claimed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |