Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 14/20 | 0.59 |
| ▸ | BCL2 | P10415 | 13/20 | 0.40 |
| ▸ | BCL2L2 | Q92843 | 6/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731200 | 0.90 | BCL2L1 (0.57) | BCL2L1BCL2BCL2L2MCL1CA1 | |
| SCHEMBL31570836 | 0.83 | BCL2L1 (0.85) | BCL2L1BCL2 | |
| SCHEMBL30405101 | 0.83 | BCL2L1 (0.85) | BCL2L1BCL2 | |
| SCHEMBL3658781 | 0.82 | BCL2L1 (0.63) | BCL2L1BCL2 | |
| SCHEMBL24633503 | 0.82 | BCL2L1 (0.87) | BCL2L1BCL2 | |
| SCHEMBL22879158 | 0.82 | BCL2L1 (0.87) | BCL2L1BCL2 | |
| SCHEMBL29424547 | 0.82 | BCL2L1 (0.87) | BCL2L1BCL2 | |
| SCHEMBL3823004 | 0.80 | BCL2L1 (0.69) | BCL2L1BCL2BCL2L2MCL1 | |
| SCHEMBL3822342 | 0.80 | BCL2L1 (0.69) | BCL2L1BCL2BCL2L2MCL1 | |
| SCHEMBL4747130 | 0.80 | BCL2L1 (0.69) | BCL2L1BCL2BCL2L2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064116-A2 | METHOD OF PREVENTING OR TREATING ORGAN, HEMATOPOIETIC STEM CELL OR BONE MARROW TRANSPLANT REJECTION | ABBOTT LABORATORIES (US) | 2008-05-29 | — | — | WO | disclosed |