Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SCN1A | P35498 | 3/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733989 | 1.00 | CHRM3 (0.69) | CHRM3MEN1KMT2AOPRM1SLC22A1 | |
| SCHEMBL4733406 | 1.00 | CHRM3 (0.69) | CHRM3MEN1KMT2AOPRM1SLC22A1 | |
| SCHEMBL4734246 | 0.99 | CHRM3 (0.67) | CHRM3MEN1KMT2AOPRM1SLC22A1 | |
| Hydrochloric Acid SCHEMBL1805907 | 0.97 | CHRM3 (0.65) | CHRM3MEN1KMT2AOPRM1SLC22A1 | |
| Hydrochloric Acid SCHEMBL8097354 | 0.95 | CHRM3 (0.62) | CHRM3MEN1KMT2AOPRM1SLC22A1 | |
| SCHEMBL14209817 | 0.94 | CHRM3 (0.64) | CHRM3MEN1KMT2AOPRM1SLC22A1 | |
| Hydrochloric Acid SCHEMBL8110706 | 0.88 | CHRM3 (0.57) | CHRM3MEN1KMT2AOPRM1SLC22A1 | |
| SCHEMBL9786866 | 0.86 | CHRM3 (0.75) | CHRM3MEN1KMT2ACHRM1MAPK1 | |
| SCHEMBL18204311 | 0.85 | MEN1 (0.55) | CHRM3MEN1KMT2AOPRM1SLC22A1 | |
| SCHEMBL8106501 | 0.84 | SCN1A (0.57) | CHRM3MEN1KMT2AOPRM1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059239-A1 | NOVEL COMPOUNDS 514 | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | disclosed |
| WO-2008059239-A1 | NOVEL COMPOUNDS 514 | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | disclosed |