Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.57 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.57 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112554 | 0.87 | RAB9A (0.54) | OPRM1CHRM3KMT2ACHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL8097354 | 0.87 | CHRM3 (0.62) | SCN1ASCN2ASCN3AOPRM1CHRM3 | |
| SCHEMBL4734246 | 0.85 | CHRM3 (0.67) | SCN1ASCN2ASCN3AOPRM1CHRM3 | |
| SCHEMBL4734319 | 0.84 | CHRM3 (0.69) | SCN1ASCN2ASCN3AOPRM1CHRM3 | |
| SCHEMBL4733406 | 0.84 | CHRM3 (0.69) | SCN1ASCN2ASCN3AOPRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL1805907 | 0.84 | CHRM3 (0.65) | SCN1ASCN2ASCN3AOPRM1CHRM3 | |
| SCHEMBL4733989 | 0.84 | CHRM3 (0.69) | SCN1ASCN2ASCN3AOPRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL8110706 | 0.81 | CHRM3 (0.57) | OPRM1CHRM3SLC22A1SLC6A4ADRA1A | |
| SCHEMBL14209817 | 0.78 | CHRM3 (0.64) | OPRM1CHRM3SLC22A1SLC6A4ADRA1A | |
| Hydrochloric Acid SCHEMBL8110612 | 0.78 | CHRM3 (0.46) | SCN1ASCN2ASCN3AOPRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124354-A | TREATMENT OF URINARY INCONTINENCE OR IRRITABLE BOWEL SYNDROME | PHARMACIA & UPJOHN AB (SE) | 2000-09-26 | — | — | US | disclosed |
| EP-0923536-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998004517-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-02-05 | — | — | WO | disclosed |