Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 5/20 | 0.54 |
| ▸ | SFRP1 | Q8N474 | 7/20 | 0.54 |
| ▸ | CCR8 | P51685 | 1/20 | 0.52 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.49 |
| ▸ | WNT3 | P56703 | 3/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8023062 | 0.94 | SFRP1 (0.51) | STSSFRP1CCR8TGFBR1GPR119 | |
| SCHEMBL4732458 | 0.92 | CCR8 (0.55) | STSSFRP1CCR8TGFBR1GPR119 | |
| SCHEMBL4736626 | 0.89 | SFRP1 (0.66) | STSSFRP1CCR8TGFBR1WNT3 | |
| SCHEMBL4734766 | 0.86 | SFRP1 (0.50) | SFRP1WNT3 | |
| SCHEMBL29716425 | 0.84 | STS (0.59) | STSSFRP1CCR8TGFBR1GPR119 | |
| SCHEMBL4281416 | 0.82 | STS (0.60) | STSSFRP1CCR8TGFBR1GPR119 | |
| SCHEMBL3810586 | 0.82 | SFRP1 (0.46) | SFRP1WNT3 | |
| SCHEMBL13932867 | 0.82 | STS (0.74) | STSSFRP1CCR8TGFBR1WNT3 | |
| SCHEMBL8022249 | 0.81 | STS (0.53) | STSSFRP1CCR8BRD4 | |
| SCHEMBL4618399 | 0.81 | SFRP1 (0.70) | SFRP1CCR8WNT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |