Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 9/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4731286 | 0.90 | SRD5A2 (0.35) | KMT2AMEN1SMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL4733347 | 0.89 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| Hydrochloric Acid SCHEMBL4729661 | 0.88 | MEN1 (0.42) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| Hydrochloric Acid SCHEMBL4735482 | 0.87 | MLYCD (0.32) | MLYCD | |
| Hydrochloric Acid SCHEMBL4783964 | 0.87 | HTR2C (0.40) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4735429 | 0.86 | PPIB (0.42) | — | |
| Hydrochloric Acid SCHEMBL4780163 | 0.85 | CYP1A2 (0.37) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| Hydrochloric Acid SCHEMBL4732641 | 0.85 | HTR2C (0.39) | PDE4APDE4BPDE4CPDE4DSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4734463 | 0.85 | CYP1A2 (0.39) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| Hydrochloric Acid SCHEMBL4782971 | 0.85 | SMPD1 (0.37) | PDE4APDE4BPDE4CPDE4DKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057497-A2 | SMALL ORGANIC MOLECULE REGULATORS OF CELL PROLIFERATION | CURIS, INC. (US) | 2008-05-15 | — | — | WO | disclosed |