Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5038584 | 0.78 | GRK6 (0.44) | CNR2ALDH1A1MEN1KMT2AALOX15 | |
| SCHEMBL2681871 | 0.73 | CNR2 (0.50) | CNR2L3MBTL1ALDH1A1KMT2AHTR2A | |
| SCHEMBL14525123 | 0.68 | HTT (0.38) | CNR2ALDH1A1 | |
| SCHEMBL19813131 | 0.67 | HTT (0.45) | NOTUML3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL16404216 | 0.66 | CNR2 (1.00) | CNR2MEN1KMT2A | |
| SCHEMBL6690870 | 0.66 | CNR2 (0.44) | CNR2L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL23441842 | 0.64 | CDK9 (0.46) | CNR2L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL29954631 | 0.64 | NOTUM (0.47) | NOTUML3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL1714277 | 0.63 | NOTUM (1.00) | NOTUML3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL23068992 | 0.62 | NOTUM (0.38) | NOTUMALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |