Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 4/20 | 0.41 |
| ▸ | BACE1 | P56817 | 4/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | FABP3 | P05413 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL4734635 | 0.80 | BACE1 (0.63) | CTSDBACE1BACE2 | |
| SCHEMBL4520922 | 0.78 | GSK3A (0.31) | BACE1 | |
| SCHEMBL8189766 | 0.74 | BACE1 (0.73) | CTSDBACE1BACE2 | |
| Hydrochloric Acid SCHEMBL4736072 | 0.74 | BACE1 (0.72) | CTSDBACE1BACE2 | |
| SCHEMBL4736296 | 0.73 | BACE1 (0.42) | CTSDBACE1BACE2 | |
| SCHEMBL4876305 | 0.70 | BACE1 (0.43) | CTSDBACE1BACE2CYP11B2 | |
| SCHEMBL4227394 | 0.70 | SCN9A (0.39) | BACE1 | |
| SCHEMBL4738814 | 0.69 | BACE1 (0.32) | CTSDBACE1BACE2 | |
| SCHEMBL4240278 | 0.68 | BACE1 (0.46) | CTSDBACE1BACE2 | |
| SCHEMBL4524491 | 0.67 | HDAC4 (0.39) | CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008076044-A1 | NOVEL 2-AMINO-5, 5-DIARYL-IMIDAZOL-4-ONES | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | claimed |