SCHEMBL4734685

SCHEMBL4734685

Cn1nnc(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC2CC(C(F)(F)F)CC2C(=O)c2ccccc2)n1

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4735589 0.82 TACR1 (0.42) CETP
SCHEMBL4786664 0.80 CETP (0.41) CETP
SCHEMBL1600908 0.77 TACR1 (0.42) CETP
SCHEMBL1600544 0.69 CETP (0.46) CETP
SCHEMBL1600511 0.69 CETP (0.46) CETP
SCHEMBL5132677 0.69 ALDH1A1 (0.42) CETP
SCHEMBL5133528 0.69 MCL1 (0.43) CETP
SCHEMBL5624431 0.69 TACR1 (0.42) CETP
SCHEMBL5050198 0.69 CETP (0.40) CETP
SCHEMBL4173923 0.69 TACR1 (0.42) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1996564-A1 DIBENZYL AMINE COMPOUNDS AND DERIVATIVES Pfizer Products Incorporated (US) 2008-12-03 EP disclosed
WO-2007105050-A1 DIBENZYL AMINE COMPOUNDS AND DERIVATIVES PFIZER PRODUCTS INC. (US) 2007-09-20 WO disclosed