Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 7/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.42 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666633 | 0.95 | ECE1 (0.45) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL4632709 | 0.95 | HDAC3 (0.45) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL4633751 | 0.95 | ECE1 (0.45) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL3943481 | 0.87 | MEN1 (0.43) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL13945806 | 0.86 | MMP9 (0.47) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL4737003 | 0.84 | KMT2A (0.49) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL4634227 | 0.84 | TACR1 (0.44) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL4634196 | 0.84 | TACR1 (0.48) | MEN1KMT2AMAPTTHRBP2RY14 | |
| SCHEMBL4633756 | 0.84 | MEN1 (0.43) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL4633723 | 0.84 | MAPT (0.44) | HDAC3HDAC1HDAC2HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071453-A1 | 1,2-DIARYLACETYLENE DERIVATIVES OF ACYLTRYPTOPHANOLS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-06-19 | — | — | WO | disclosed |