SCHEMBL4734844

SCHEMBL4734844

CCCCCCCCCCCCCCCC(=O)OC1CC[C@@]2(C)C(CC[C@H]3[C@@H]4CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]4(C)CC[C@@H]32)C1

nearest known ligand 0.66

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
VDR P11473 3/20 0.59
USP2 O75604 1/20 0.59
ST6GAL1 P15907 1/20 0.55
CDC25A P30304 2/20 0.54
ABCC4 O15439 1/20 0.53
POLA1 P09884 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4740092 1.00 VDR (0.59) VDRUSP2ST6GAL1CDC25AABCC4
SCHEMBL4740093 1.00 VDR (0.59) VDRUSP2ST6GAL1CDC25AABCC4
SCHEMBL4782228 1.00 VDR (0.59) VDRUSP2ST6GAL1CDC25AABCC4
SCHEMBL14580604 1.00 VDR (0.59) VDRUSP2ST6GAL1CDC25AABCC4
SCHEMBL4737067 1.00 VDR (0.59) VDRUSP2ST6GAL1CDC25AABCC4
SCHEMBL4734954 1.00 VDR (0.59) VDRUSP2ST6GAL1CDC25AABCC4
SCHEMBL4734841 1.00 VDR (0.59) VDRUSP2ST6GAL1CDC25AABCC4
SCHEMBL1169827 1.00 VDR (0.59) VDRUSP2ST6GAL1CDC25AABCC4
SCHEMBL4734416 1.00 VDR (0.59) VDRUSP2ST6GAL1CDC25AABCC4
SCHEMBL4734953 1.00 VDR (0.59) VDRUSP2ST6GAL1CDC25AABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008077247-A1 COATINGS FOR IMPLANTABLE MEDICAL DEVICES COMPRISING CHOLESTEROL MIV THERAPEUTICS INC. (CA) 2008-07-03 WO disclosed
EP-0982315-B1 Preparation of sterol and stanol esters MCNEIL PPC INC (US) 2006-04-12 EP disclosed
US-6184397-B1 LARGE SCALE PRODUCTION OF ESTERS IN HIGH YIELDS BY THE ESTERIFICATION OF STEROLS USING AN ACID OR BASIC CATALYST AND A DECOLORING AGENT; SOLVENT-AND MINERAL ACID-FREE; FOODGRADE; ANTICHOLESTEROL AGENTS, E.G. B-SITOSTEROL FATTY ESTER MCNEIL-PPC, INC. 2001-02-06 US disclosed
US-6147236-A Preparation of sterol and stanol-esters MCNEIL-PPC, INC. (US) 2000-11-14 US disclosed
EP-0982316-A2 Preparation of sterol and stanol-esters McNEIL-PPC, INC. (US) 2000-03-01 EP disclosed
EP-0982315-A2 Preparation of sterol and stanol esters McNEIL-PPC, INC. (US) 2000-03-01 EP disclosed
US-5892068-A Preparation of sterol and stanol-esters MCNEIL-PPC, INC. (US) 1999-04-06 US disclosed