Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 16/20 | 0.73 |
| ▸ | CNR1 | P21554 | 5/20 | 0.73 |
| ▸ | MOK | Q9UQ07 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733207 | 0.92 | CNR2 (0.69) | CNR2CNR1 | |
| SCHEMBL14206965 | 0.91 | CNR2 (0.72) | CNR2CNR1 | |
| SCHEMBL4729995 | 0.88 | CNR2 (0.69) | CNR2CNR1 | |
| SCHEMBL4732946 | 0.85 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL4731520 | 0.84 | CNR2 (0.79) | CNR2CNR1 | |
| SCHEMBL4730649 | 0.84 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL4729964 | 0.84 | CNR2 (0.82) | CNR2CNR1 | |
| SCHEMBL14206427 | 0.83 | CNR2 (0.80) | CNR2CNR1 | |
| SCHEMBL4729604 | 0.83 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL4730516 | 0.82 | CNR2 (0.76) | CNR2CNR1MOK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | claimed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |