Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MYOC | Q99972 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | TSPO | P30536 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12569539 | 0.86 | MEN1 (0.53) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL15644535 | 0.84 | KMT2A (0.52) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL29559776 | 0.84 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL22897575 | 0.84 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL21568091 | 0.82 | MEN1 (0.58) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL4001716 | 0.80 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL13170071 | 0.80 | MEN1 (0.57) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL5391295 | 0.80 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HTTKMT2AMAPT | |
| SCHEMBL15998602 | 0.80 | KMT2A (0.48) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL20825702 | 0.79 | MEN1 (0.56) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008070891-A1 | LIGANDS FOR THE MODULATION OF ECDYSONE RECEPTORS AND CONTROL OF INSECT GROWTH | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008070934-A1 | INHIBITION OF INVERTEBRATES USING LIGANDS THAT MODULATE ECDYSONE RECEPTORS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2008-06-19 | — | — | WO | disclosed |