Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 13/20 | 0.53 |
| ▸ | PGR | P06401 | 8/20 | 0.53 |
| ▸ | NR3C2 | P08235 | 6/20 | 0.40 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.36 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.36 |
| ▸ | DHPS | P49366 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4628515 | 0.86 | NR3C1 (0.45) | NR3C1PGRNR3C2TRPV1 | |
| SCHEMBL4824963 | 0.81 | NR3C1 (0.62) | NR3C1PGRNR3C2TRPV1 | |
| SCHEMBL4630424 | 0.79 | NR3C1 (0.45) | NR3C1PGRNR3C2 | |
| SCHEMBL6406146 | 0.78 | NR3C1 (0.39) | NR3C1PGRNR3C2TRPV1 | |
| SCHEMBL6405688 | 0.77 | NR3C1 (0.43) | NR3C1PGRNR3C2 | |
| SCHEMBL6404639 | 0.77 | NR3C1 (0.47) | NR3C1PGRNR3C2 | |
| SCHEMBL3533407 | 0.77 | NR3C1 (0.43) | NR3C1PGRNR3C2 | |
| SCHEMBL4629925 | 0.77 | NR3C1 (0.53) | NR3C1 | |
| SCHEMBL6408229 | 0.76 | NR3C1 (0.42) | NR3C1PGRNR3C2 | |
| SCHEMBL4628801 | 0.75 | NR3C1 (0.44) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008055709-A1 | INDAZOLE AND INDOLE DERIVATIVES AS ANTI -INFLAMMATORY AGENTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-05-15 | — | — | WO | disclosed |