Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 10/20 | 0.43 |
| ▸ | CAPN9 | O14815 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSH | P09668 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15171440 | 0.90 | SUCNR1 (0.52) | CAPN1CAPN9CTSBMAPK1SUCNR1 | |
| SCHEMBL31502886 | 0.78 | SUCNR1 (0.65) | SUCNR1TSHRLMNAALDH1A1 | |
| SCHEMBL16466637 | 0.77 | CHRNB2 (0.37) | CAPN1CAPN9CTSBMAPK1CHRNB2 | |
| SCHEMBL16639440 | 0.77 | CHRNB2 (0.37) | CAPN1CAPN9CTSBMAPK1CHRNB2 | |
| SCHEMBL16488393 | 0.71 | CHRNB2 (0.36) | CAPN1CAPN9CTSBMAPK1CHRNB2 | |
| SCHEMBL11183116 | 0.71 | CAPN1 (0.40) | CAPN1CAPN9CTSBMAPK1CHRNB2 | |
| SCHEMBL7615476 | 0.70 | CAPN1 (0.58) | CAPN1CAPN9CTSBMAPK1SUCNR1 | |
| SCHEMBL11063045 | 0.68 | CAPN1 (0.68) | CAPN1CAPN9CTSBMAPK1CTSK | |
| SCHEMBL6741406 | 0.67 | CAPN1 (0.58) | CAPN1CAPN9CTSBMAPK1CTSK | |
| SCHEMBL20179145 | 0.67 | CAPN1 (0.66) | CAPN1CAPN9CTSBMAPK1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008078249-A1 | ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-07-03 | — | — | WO | disclosed |