Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17365726 | 0.80 | GRIN1 (0.34) | MEN1ALDH1A1LMNAHSP90AA1PKM | |
| SCHEMBL20270351 | 0.76 | ALOX15 (0.34) | MEN1ALDH1A1LMNAHSP90AA1PKM | |
| SCHEMBL20270866 | 0.76 | DRD1 (0.32) | DRD1 | |
| SCHEMBL12474304 | 0.76 | ALOX15 (0.39) | MEN1ALDH1A1LMNAHSP90AA1PKM | |
| SCHEMBL16950691 | 0.75 | DRD1 (0.33) | MEN1ALDH1A1LMNAHSP90AA1PKM | |
| SCHEMBL27982688 | 0.73 | POLB (0.36) | MEN1ALDH1A1LMNAKMT2APDE2A | |
| SCHEMBL12474327 | 0.73 | APP (0.31) | — | |
| SCHEMBL14596841 | 0.71 | ALOX15 (0.42) | MEN1ALDH1A1LMNAHSP90AA1PKM | |
| SCHEMBL14843593 | 0.71 | TAAR1 (0.34) | — | |
| SCHEMBL4189560 | 0.71 | MEN1 (0.36) | MEN1ALDH1A1LMNAPKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343775-B1 | PIPERAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-06-04 | — | — | EP | claimed |