⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1240653 | 0.97 | CYP1A2 (0.56) | — | |
| SCHEMBL2533487 | 0.97 | CYP1A2 (0.56) | — | |
| SCHEMBL330340 | 0.97 | CYP1A2 (0.56) | — | |
| SCHEMBL473467 | 0.94 | — | — | |
| SCHEMBL473617 | 0.92 | SIGMAR1 (0.52) | — | |
| SCHEMBL5540630 | 0.89 | SIGMAR1 (0.56) | — | |
| SCHEMBL329924 | 0.89 | SIGMAR1 (0.56) | — | |
| SCHEMBL5313489 | 0.89 | SIGMAR1 (0.56) | — | |
| SCHEMBL2078510 | 0.89 | SIGMAR1 (0.56) | — | |
| SCHEMBL5534476 | 0.89 | SIGMAR1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 303 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190127413-A1 | Compositions and Methods for Non-Toxic Delivery of Antiprogestins | ALLERGAN PHARMACEUTICALS INTERNATIONAL LIMITED (IE) | 2019-05-02 | — | — | US | claimed |
| US-8865200-B2 | Sustained release compositions containing progesterone receptor modulators | LABORATOIRE HRA PHARMA (FR) | 2014-10-21 | — | — | US | claimed |
| US-20140107089-A1 | STRUCTURAL MODIFICATION OF 19-NORPROGESTERONE I: 17-ALPHA-SUBSTITUTED-11-BETA-SUBSTITUTED-4-ARYL AND 21-SUBSTITUTED 19-NORPREGNADIENEDIONE AS NEW ANTIPROGESTATIONAL AGENTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERV (US) | 2014-04-17 | — | — | US | claimed |
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| EP-2550288-A1 | COMPOSITIONS AND METHODS FOR NON-TOXIC DELIVERY OF ANTIPROGESTINS | Repros Therapeutics Inc. (US) | 2013-01-30 | — | — | EP | claimed |
| US-20130018027-A1 | COMPOSITIONS AND METHODS FOR NON-TOXIC DELIVERY OF ANTIPROGESTINS | REPROS THERAPEUTICS INC. (US) | 2013-01-17 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |
| WO-2011119194-A1 | COMPOSITIONS AND METHODS FOR NON-TOXIC DELIVERY OF ANTIPROGESTINS | REPROS THERAPEUTICS INC. (US) | 2011-09-29 | — | — | WO | claimed |
| US-8003629-B2 | 21-substituted progesterone derivatives as new antiprogestational agents | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2011-08-23 | — | — | US | claimed |
| EP-2348030-A2 | 17-Alpha-substituted-11-beta-substituted-4-aryl and 21-substituted 19-norpregnadienedione as antiprogestational agents | The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services (US) | 2011-07-27 | — | — | EP | claimed |
| EP-1265911-A2 | 17-ALPHA-SUBSTITUTED-11-BETA-SUBSTITUTED-4-ARYL AND 21-SUBSTITUTED 19-NORPREGNADIENEDIONE AS ANTIPROGESTATIONAL AGENTS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2002-12-18 | — | — | EP | claimed |
| US-20020183532-A1 | Bioavailable prodrugs of androgenic steroids and related method | BIOTEST LABORATORIES, LLC | 2002-12-05 | — | — | US | claimed |
| US-20020025951-A1 | 21-SUBSTITUTED PROGESTERONE DERIVATIVES AS NEW ANTIPROGESTATIONAL AGENTS | NATIONAL INSTITUTES OF HEALTH | 2002-02-28 | — | — | US | claimed |
| WO-2001074840-A2 | 17-ALPHA-SUBSTITUTED-11-BETA-SUBSTITUTED-4-ARYL AND 21-SUBSTITUTED 19-NORPREGNA 21-SUBSTITUTED 19-NORPREGNADIENEDIONE AS ANTIPROGESTATIONAL AGENTS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF HEALTH AND HUMAN SERVICES (US) | 2001-10-11 | — | — | WO | claimed |
| EP-0900234-B1 | 21-SUBSTITUTED PROGESTERONE DERIVATIVES AS NEW ANTIPROGESTATIONAL AGENTS | US GOV HEALTH & HUMAN SERV (US) | 2000-07-05 | — | — | EP | claimed |
| EP-0900234-A1 | 21-SUBSTITUTED PROGESTERONE DERIVATIVES AS NEW ANTIPROGESTATIONAL AGENTS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-03-10 | — | — | EP | claimed |
| WO-1997041145-A1 | 21-SUBSTITUTED PROGESTERONE DERIVATIVES AS NEW ANTIPROGESTATIONAL AGENTS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1997-11-06 | — | — | WO | claimed |
| EP-0254588-B1 | Imidazo[4,5-b] pyridine compounds, process for preparing same and pharmaceutical compositions containing same | TOKYO TANABE COMPANY LIMITED (JP) | 1992-01-15 | — | — | EP | claimed |
| US-4808596-A | STORAGE STABLE, ANTIULCER AGENTS | TOKYO TANABE COMPANY, LTD. (JP) | 1989-02-28 | — | — | US | claimed |
| EP-0254588-A1 | Imidazo[4,5-b] pyridine compounds, process for preparing same and pharmaceutical compositions containing same | TOKYO TANABE COMPANY LIMITED (JP) | 1988-01-27 | — | — | EP | claimed |