Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.49 |
| ▸ | BRD3 | Q15059 | 4/20 | 0.49 |
| ▸ | BRD2 | P25440 | 3/20 | 0.49 |
| ▸ | WNT3 | P56703 | 1/20 | 0.48 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732685 | 0.87 | SFRP1 (0.53) | BRD4BRD3BRD2WNT3SFRP1 | |
| SCHEMBL4736004 | 0.84 | SFRP1 (0.44) | WNT3SFRP1 | |
| SCHEMBL4732044 | 0.83 | SFRP1 (0.53) | BRD4BRD3BRD2WNT3SFRP1 | |
| SCHEMBL4847916 | 0.82 | SFRP1 (0.52) | BRD4WNT3SFRP1 | |
| SCHEMBL4735520 | 0.82 | SFRP1 (0.55) | BRD4BRD3BRD2WNT3SFRP1 | |
| SCHEMBL4734668 | 0.79 | SFRP1 (0.53) | BRD4BRD3BRD2WNT3SFRP1 | |
| SCHEMBL4732944 | 0.79 | SFRP1 (0.62) | BRD4BRD3BRD2WNT3SFRP1 | |
| SCHEMBL4731736 | 0.79 | SFRP1 (0.54) | BRD4BRD3BRD2WNT3SFRP1 | |
| SCHEMBL4780456 | 0.79 | POLB (0.44) | L3MBTL1ALDH1A1GAAHTT | |
| SCHEMBL4780458 | 0.79 | POLB (0.44) | L3MBTL1ALDH1A1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | claimed |
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |