SCHEMBL4736026

SCHEMBL4736026

CCOC(CC)c1ccc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CETP P11597 18/20 0.42
TACR1 P25103 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1600339 0.92 CETP (0.43) CETPTACR1
SCHEMBL1601476 0.92 CETP (0.43) CETPTACR1
SCHEMBL1600342 0.92 CETP (0.43) CETPTACR1
SCHEMBL1600334 0.90 TACR1 (0.44) CETPTACR1
SCHEMBL1600335 0.90 TACR1 (0.44) CETPTACR1
SCHEMBL1600685 0.90 TACR1 (0.44) CETPTACR1
SCHEMBL1600317 0.89 CETP (0.41) CETPTACR1
SCHEMBL1600964 0.88 CETP (0.43) CETP
SCHEMBL1600307 0.86 CETP (0.45) CETP
SCHEMBL4186468 0.86 CETP (0.44) CETPTACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1996564-A1 DIBENZYL AMINE COMPOUNDS AND DERIVATIVES Pfizer Products Incorporated (US) 2008-12-03 EP claimed
WO-2007105050-A1 DIBENZYL AMINE COMPOUNDS AND DERIVATIVES PFIZER PRODUCTS INC. (US) 2007-09-20 WO claimed