Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.44 |
| ▸ | CETP | P11597 | 16/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1600334 | 1.00 | TACR1 (0.44) | TACR1CETPKCNH2 | |
| SCHEMBL1600335 | 1.00 | TACR1 (0.44) | TACR1CETPKCNH2 | |
| SCHEMBL4736026 | 0.90 | CETP (0.42) | TACR1CETP | |
| SCHEMBL1601476 | 0.88 | CETP (0.43) | TACR1CETP | |
| SCHEMBL1600339 | 0.88 | CETP (0.43) | TACR1CETP | |
| SCHEMBL1600342 | 0.88 | CETP (0.43) | TACR1CETP | |
| SCHEMBL1600850 | 0.86 | TACR1 (0.43) | TACR1CETP | |
| SCHEMBL1600654 | 0.86 | TACR1 (0.43) | TACR1CETP | |
| SCHEMBL1600904 | 0.86 | TACR1 (0.43) | TACR1CETP | |
| SCHEMBL4975007 | 0.84 | TACR1 (0.49) | TACR1CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919506-B2 | Dibenzyl amine compounds and derivatives | PFIZER INC. (US) | 2011-04-05 | — | — | US | claimed |
| US-20070213371-A1 | Dibenzyl Amine Compounds and Derivatives | PFIZER INC | 2007-09-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213371-A1 | Dibenzyl Amine Compounds and Derivatives | APOB, LDLR, CETP | TACR1 2334/4885CETP 3/4885KCNH2 4155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.