Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 17/20 | 0.67 |
| ▸ | WNT3 | P56703 | 13/20 | 0.67 |
| ▸ | CCR8 | P51685 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736057 | 1.00 | SFRP1 (0.67) | SFRP1WNT3CCR8EPHX2DPP4 | |
| SCHEMBL4736186 | 0.90 | SFRP1 (0.66) | SFRP1WNT3CCR8 | |
| SCHEMBL4732800 | 0.90 | SFRP1 (0.66) | SFRP1WNT3CCR8 | |
| SCHEMBL4732809 | 0.90 | SFRP1 (0.66) | SFRP1WNT3CCR8 | |
| SCHEMBL4736183 | 0.90 | SFRP1 (0.66) | SFRP1WNT3CCR8 | |
| SCHEMBL4734132 | 0.88 | SFRP1 (0.64) | SFRP1WNT3CCR8 | |
| SCHEMBL4734127 | 0.88 | SFRP1 (0.64) | SFRP1WNT3CCR8 | |
| SCHEMBL4735028 | 0.87 | SFRP1 (0.75) | SFRP1WNT3CCR8 | |
| SCHEMBL4737282 | 0.87 | SFRP1 (0.63) | SFRP1WNT3CCR8 | |
| SCHEMBL4735675 | 0.87 | SFRP1 (0.70) | SFRP1WNT3CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | claimed |
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |