Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.61 |
| ▸ | PPARG | P37231 | 11/20 | 0.61 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738651 | 0.92 | PPARA (0.68) | PPARAPPARGCYSLTR1CYSLTR2LTB4R | |
| SCHEMBL4740467 | 0.91 | PPARA (0.63) | PPARAPPARGCYSLTR1CYSLTR2LTB4R | |
| SCHEMBL4740472 | 0.89 | PPARA (0.63) | PPARAPPARGCYSLTR1CYSLTR2LTB4R | |
| SCHEMBL4738592 | 0.88 | PPARA (0.68) | PPARAPPARGCYSLTR1CYSLTR2 | |
| SCHEMBL4739535 | 0.88 | PPARA (0.65) | PPARAPPARGCYSLTR1CYSLTR2LTB4R | |
| SCHEMBL4736308 | 0.85 | PPARA (0.65) | PPARAPPARGCYSLTR1CYSLTR2 | |
| SCHEMBL4738676 | 0.83 | PPARA (0.63) | PPARAPPARGCYSLTR1CYSLTR2 | |
| SCHEMBL4740397 | 0.83 | PPARG (0.45) | PPARAPPARGCYSLTR1CYSLTR2PPARD | |
| SCHEMBL4738692 | 0.81 | PPARA (0.65) | PPARAPPARGCYSLTR1CYSLTR2 | |
| SCHEMBL4739882 | 0.80 | PPARA (0.59) | PPARAPPARGLTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081096-A2 | QUINOLINYL DERIVATIVES, METHOD FOR PREPARING SAME, PHARMACEUTIC COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS HYPOGLYCEMIANT AND HYPOLIPEMIANT AGENTS | LES LABORATOIRES SERVIER (FR) | 2008-07-10 | — | — | WO | disclosed |