Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.59 |
| ▸ | PPARG | P37231 | 10/20 | 0.59 |
| ▸ | LTB4R | Q15722 | 9/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782940 | 0.87 | PPARG (0.45) | PPARAPPARGLTB4R | |
| SCHEMBL4738592 | 0.82 | PPARA (0.68) | PPARAPPARG | |
| SCHEMBL4739535 | 0.81 | PPARA (0.65) | PPARAPPARGLTB4R | |
| SCHEMBL4740472 | 0.80 | PPARA (0.63) | PPARAPPARGLTB4R | |
| SCHEMBL4740467 | 0.80 | PPARA (0.63) | PPARAPPARGLTB4R | |
| SCHEMBL4736217 | 0.80 | PPARA (0.61) | PPARAPPARGLTB4R | |
| SCHEMBL4738676 | 0.78 | PPARA (0.63) | PPARAPPARG | |
| SCHEMBL4857496 | 0.73 | PPARG (0.42) | PPARAPPARG | |
| SCHEMBL4786066 | 0.71 | PPARG (0.40) | PPARAPPARG | |
| SCHEMBL4887675 | 0.70 | PPARG (0.38) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081096-A2 | QUINOLINYL DERIVATIVES, METHOD FOR PREPARING SAME, PHARMACEUTIC COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS HYPOGLYCEMIANT AND HYPOLIPEMIANT AGENTS | LES LABORATOIRES SERVIER (FR) | 2008-07-10 | — | — | WO | disclosed |