Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 13/20 | 0.58 |
| ▸ | PTPN2 | P17706 | 7/20 | 0.56 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.54 |
| ▸ | PYGM | P11217 | 1/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736769 | 0.86 | PTPN1 (0.76) | PTPN1PTPN2PTPN6AKR1B10AKR1B1 | |
| SCHEMBL4735934 | 0.86 | PTPN1 (0.76) | PTPN1PTPN2PTPN6AKR1B10AKR1B1 | |
| SCHEMBL4734341 | 0.85 | PTPN1 (0.65) | PTPN1PTPN2AKR1B10AKR1B1PYGM | |
| SCHEMBL4736389 | 0.83 | PTPN1 (0.73) | PTPN1PTPN2AKR1B10AKR1B1PYGM | |
| SCHEMBL5799378 | 0.83 | PTPN1 (0.72) | PTPN1PTPN2PTPN6AKR1B10AKR1B1 | |
| SCHEMBL5795816 | 0.83 | PTPN1 (0.72) | PTPN1PTPN2PTPN6AKR1B10AKR1B1 | |
| SCHEMBL5799434 | 0.83 | PTPN1 (0.72) | PTPN1PTPN2PTPN6AKR1B10AKR1B1 | |
| SCHEMBL3291508 | 0.82 | USP2 (0.70) | PTPN1PTPN2PTPN6AKR1B10AKR1B1 | |
| SCHEMBL2984032 | 0.81 | PTPN1 (0.61) | PTPN1PTPN2PTPN6AKR1B10AKR1B1 | |
| SCHEMBL4733506 | 0.78 | PTPN1 (0.49) | PTPN1PTPN2PTPN6AKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071169-A2 | METHOD FOR THE PRODUCTION OF SPECIFIC INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE, IN PARTICULAR TYPE 1 WITH BASIC NOR-OLEANAN OR NOR-URSAN FRAMEWORKS | UNIVERSITÄTSKLINIKUM SCHLESWIG-HOLSTEIN (DE) | 2008-06-19 | — | — | WO | disclosed |