Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.65 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.65 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.59 |
| ▸ | PYGM | P11217 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.59 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.59 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736389 | 0.95 | PTPN1 (0.73) | PTPN1ALOX5AKR1B10PYGMAKR1B1 | |
| SCHEMBL4736336 | 0.85 | PTPN1 (0.58) | PTPN1AKR1B10PYGMAKR1B1PTPN2 | |
| SCHEMBL4736769 | 0.85 | PTPN1 (0.76) | PTPN1AKR1B10AKR1B1PTPN2GPBAR1 | |
| SCHEMBL4735934 | 0.85 | PTPN1 (0.76) | PTPN1AKR1B10AKR1B1PTPN2GPBAR1 | |
| SCHEMBL4734338 | 0.84 | PTPN1 (0.68) | PTPN1ALOX5AKR1B10PYGMAKR1B1 | |
| SCHEMBL4736386 | 0.83 | PTPN1 (0.77) | PTPN1ALOX5AKR1B10PYGMAKR1B1 | |
| SCHEMBL4735959 | 0.82 | PTPN1 (0.54) | PTPN1ALOX5AKR1B10PYGMAKR1B1 | |
| SCHEMBL5800384 | 0.82 | PTPN1 (0.76) | PTPN1ALOX5AKR1B10PYGMAKR1B1 | |
| SCHEMBL5800381 | 0.82 | PTPN1 (0.76) | PTPN1ALOX5AKR1B10PYGMAKR1B1 | |
| SCHEMBL4734806 | 0.80 | GABRP (0.75) | PTPN1ALOX5AKR1B10PYGMAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071169-A2 | METHOD FOR THE PRODUCTION OF SPECIFIC INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE, IN PARTICULAR TYPE 1 WITH BASIC NOR-OLEANAN OR NOR-URSAN FRAMEWORKS | UNIVERSITÄTSKLINIKUM SCHLESWIG-HOLSTEIN (DE) | 2008-06-19 | — | — | WO | claimed |
| WO-2008071169-A2 | METHOD FOR THE PRODUCTION OF SPECIFIC INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE, IN PARTICULAR TYPE 1 WITH BASIC NOR-OLEANAN OR NOR-URSAN FRAMEWORKS | UNIVERSITÄTSKLINIKUM SCHLESWIG-HOLSTEIN (DE) | 2008-06-19 | — | — | WO | disclosed |