Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4177178 | 0.94 | FASN (0.54) | FASN | |
| SCHEMBL4183556 | 0.86 | FASN (0.61) | FASN | |
| SCHEMBL4736791 | 0.85 | FASN (0.46) | FASN | |
| SCHEMBL4169820 | 0.82 | FASN (0.64) | FASN | |
| SCHEMBL4190060 | 0.81 | PKM (0.54) | FASN | |
| SCHEMBL4183378 | 0.80 | FASN (0.60) | FASN | |
| SCHEMBL4186608 | 0.79 | FASN (0.61) | FASN | |
| SCHEMBL4176263 | 0.79 | FASN (0.65) | FASN | |
| SCHEMBL4182789 | 0.78 | FASN (0.56) | FASN | |
| SCHEMBL13890623 | 0.78 | FASN (0.59) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075070-A1 | SULFONAMIDE DERIVATIVES FOR THERAPEUTIC USE AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |